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CRP

The Quantum Blue CRP test allows for a rapid determination of serum CRP within 22 minutes. It is an ideal tool to accompany the calprotectin determination for establishing an IBD patient inflammation profile during the course of the disease. The combination of the two markers has shown to increase the specificity for detecting inflammation in Crohn’s disease. The ease of use and speed of these two tests on the Quantum Blue® platform make this technology a very convenient addition to the therapy monitoring chronic inflammation of the gut.

 

C-Reactive Protein as marker for IBD

C-reactive protein (CRP) is produced by hepatocytes upon stimulation by the pro-inflammatory cytokines IL-1α, IL-6 and TNFα. It is therefore a widely used marker for inflammation and has also been shown in inflammatory bowel disease (IBD). Besides calprotectin, CRP serves as a reliable marker for the clinical course and helps to predict relapses at the onset. Literature has shown a positive correlation between CRP levels, number of relapses and severity (Koelewijn et al., 2008, World J Gastroenterol).

 

Quantum Blue® C-Reactive Protein (CRP)

The Quantum Blue® C-Reactive Protein (CRP) lateral flow assay is a sandwich-type immunoassay designed for the quantitative determination of CRP in human serum in combination with the BÜHLMANN Quantum Blue® reader. Less than 50 µl serum is required to perform the lateral flow test for CRP. The intended use of CRP Quantum Blue® is the monitoring of IBD with combined determination of calprotectin thereby supporting safe and accurate diagnosis as well as disease monitoring of IBD.

 

Quantum Blue® C-Reactive Protein (CRP) Product Information

Method Lateral Flow
Time to Result 22 min
Sample Type Serum (<50 µl)
Assay Range 1.0 mg/L – 25 mg/L
Sensitivity <1.0 mg/l
Order Code LF-CRP25
  CE

 

 

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